| Primary Identifier | MGI:97774 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 19132 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be a structural constituent of cytoskeleton. Acts upstream of or within intermediate filament cytoskeleton organization. Located in C-fiber; neurofilament; and photoreceptor outer segment membrane. Is expressed in several structures, including adrenal gland; alimentary system; diaphragm; nervous system; and olfactory system. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 1. Orthologous to human PRPH (peripherin). PHENOTYPE: Homozygous null mice showed no overt phenotype up to 14 months of age. While overall structure, number, and caliber of large myelinated axons was normal, mice had reduced numbers of a small subset of unmelinated sensory axons. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
