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Protein Domain : Baculoviral IAP repeat-containing protein 6

Primary Identifier  IPR022103 Type  Family
Short Name  BIRC6
description  Baculoviral IAP repeat-containing protein 6 (BIRC6, also known as BRUCE) is an anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase []. It has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase []. It is crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification [].

0 Child Features

0 Parent Features

5 Protein Domain Regions