Primary Identifier | MGI:3851764 | Allele Type | Chemically induced (ENU) |
Gene | Rag1 | Inheritance Mode | Recessive |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false | Project Collection | Beutler Mutagenetix |
molecularNote | This mutation was identified in a blood screen of G3 progeny of an ENU mutagenized male mouse. The mutation comprises a C to A transversion at nucleotide position 2783 of the gene. It converts the codon encoding tyrosine at amino acid position 886, in the C-terminal region of the core protein sequence, to a translation termination codon (Y886Ter). This is predicted to truncate the core by 123 and the full length protein by 155 amino acids. |