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Allele : Rag1<m1Btlr> recombination activating 1; mutation 1, Bruce Beutler

Primary Identifier  MGI:3851764 Allele Type  Chemically induced (ENU)
Gene  Rag1 Inheritance Mode  Recessive
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false Project Collection  Beutler Mutagenetix
molecularNote  This mutation was identified in a blood screen of G3 progeny of an ENU mutagenized male mouse. The mutation comprises a C to A transversion at nucleotide position 2783 of the gene. It converts the codon encoding tyrosine at amino acid position 886, in the C-terminal region of the core protein sequence, to a translation termination codon (Y886Ter). This is predicted to truncate the core by 123 and the full length protein by 155 amino acids.
  • mutations:
  • Single point mutation
  • synonyms:
  • Rag1<maladaptive>,
  • maladaptive,
  • Rag1<maladaptive>,
  • maladaptive
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele