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Allele : Prmt9<em1(IMPC)J> protein arginine methyltransferase 9; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6104244 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Prmt9
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences TGTTACCATGAGCCAAACCC, AACGTGAATGAGGACTTCCT, GAGATAATCCTATACTCATG and ATCTCTATCAGGCCAAAGCA, which resulted in a 355 bp deletion beginning at Chromosome 8 positive strand position 77,555,474 bp and ending after 77,555,828 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001258787 (exon 2) and 206 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 63 and early truncation 4 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele