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Protein Coding Gene : Kel Kell blood group

Primary Identifier  MGI:1346053 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  23925
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 5.4.0)

Enables metallopeptidase activity. Acts upstream of or within several processes, including intracellular monoatomic cation homeostasis; regulation of axon diameter; and skeletal muscle fiber development. Located in membrane. Orthologous to human KEL (Kell metallo-endopeptidase (Kell blood group)).
PHENOTYPE: Mice homozygous for a null allele exhibit decreased heart rate, altered hematological parameters and ECG waveform features, decreased erythrocyte Mg2+ and K+ ion content, mild motor deficits, and giant axon changes with varying degrees of paranodal demyelination in the spinal cord and sciatic nerve. [provided by MGI curators]
  • synonyms:
  • Kell blood group,
  • Kel,
  • CD238

Features --> Cross References


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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features


Gene --> Proteins


Mouse features --> Functions (GO terms)


Genes --> Homologs


5 Pathways

35 Targeted By

Gene --> Protein-Protein Interactions


Gene --> Expression annotations


Genes/Features --> Phenotypes (MP terms)


Mouse features --> Human diseases


Mouse features --> Publications



0 Driver For