| Primary Identifier | MGI:2140844 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 100609 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables rRNA (cytosine-C5-)-methyltransferase activity. Involved in several processes, including central nervous system development; rRNA base methylation; and regulation of myelination. Predicted to be located in nucleoplasm. Predicted to be active in nucleolus. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and sensory organ. Orthologous to several human genes including NSUN5 (NOP2/Sun RNA methyltransferase 5). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired spatial working memory and learning with decreased LTP and reduced OPC proliferation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
