| Primary Identifier | IPR031814 | Type | Domain |
| Short Name | ALG11_N |
| description | GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (ALG11) is involved in N-linked oligosaccharide synthesis []. It is highly conserved, with homologues in fission yeast, worms, flies, and plants []. It catalyses the sequential transfer of two alpha1,2-linked mannose residues from GDP-mannose to Man3GlcNAc2-PP-Dol forming the Man5GlcNAc2-PP-Dol intermediate at the cytosolic side of the ER before flipping to the luminal side. Alg11 contains three hydrophobic transmembrane-spanning helices found in the N-terminal domain []. |
