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Publication : Modulation of mRNA levels in the presence of thymocytes and genome mapping for a set of genes expressed in mouse thymic epithelial cells.

First Author  Rocha D Year  1997
Journal  Immunogenetics Volume  46
Issue  2 Pages  142-51
PubMed ID  9162101 Mgi Jnum  J:41180
Mgi Id  MGI:893259 Doi  10.1007/s002510050253
Citation  Rocha D, et al. (1997) Modulation of mRNA levels in the presence of thymocytes and genome mapping for a set of genes expressed in mouse thymic epithelial cells. Immunogenetics 46(2):142-51
abstractText  Modulation of gene expression in mouse thymic epithelium upon culture in the presence of thymocytes (coculture) was studied by comparison of hybridization signatures on a set of nearly 5000 mouse thymus cDNA clones. Forty-nine differentially expressed clones (usually down-regulated in coculture) were characterized by tag sequencing. Many of them corresponded to entities that had not been described previously in the mouse, and were further characterized by genome mapping. This set of genes appears to be involved in growth regulation and differentiation within the thymus.
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