Primary Identifier | MGI:7378548 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Setd1a |
Strain of Origin | (C57BL/6 x DBA/2)F2 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology targeted exon 15 and generated an 8 bp deletion that causes a frameshift and premature translation termination, mimicking the human loss-of-function mutations in patients with schizophrenia. |