Primary Identifier | MGI:6284840 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Dock2 |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=4040 |
molecularNote | ENU-induced T to C transition at base pair 34,687,538 (v38) on chromosome 11, or base pair 96,372 in the GenBank genomic region NC_000077 for Dock2. The mutation corresponds to residue 2,319 in the mRNA sequence NM_178666 within exon 22 of 52 total exons. The mutation results in a phenylalanine to serine substitution at position 746 (F746S) in the DOCK2 protein. |