| First Author | Worley P | Year | 2013 |
| Journal | MGI Direct Data Submission | Mgi Jnum | J:198768 |
| Mgi Id | MGI:5499103 | Citation | Worley P (2013) Haploinsufficiency of Shank3 causes Autism-like phenotypes in mice. MGI Direct Data Submission |
| abstractText | The data reported for this allele were originally described in Bangash MA, Park JM, Melnikova T, Wang D, Jeon SK, Lee D, Syeda S, Kim J, Kouser M, Schwartz J, Cui Y, Zhao X, Speed HE, Kee SE, Tu JC, Hu JH, Petralia RS, Linden DJ, Powell CM, Savonenko A, Xiao B, Worley PF. "Enhanced polyubiquitination of Shank3 and NMDA receptor in a mouse model of autism." Cell. 2011 May 27;145(5):758-72. PMID:21565394. This paper was retracted (PMID:23332766); however, the prinicpal investigator has confirmed the validity of the data related to the molecular gene targeting and the phenotypic description of the mutant mice carrying the Shank3 allele. Please see the retraction notes for further details about the data in the original paper. |
