| First Author | Díaz-Alonso J | Year | 2020 |
| Journal | Elife | Volume | 9 |
| PubMed ID | 32831170 | Mgi Jnum | J:306675 |
| Mgi Id | MGI:6705415 | Doi | 10.7554/eLife.58042 |
| Citation | Diaz-Alonso J, et al. (2020) Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit. Elife 9:e58042 |
| abstractText | We tested the proposal that the C-terminal domain (CTD) of the AMPAR subunit GluA1 is required for LTP. We found that a knock-in mouse lacking the CTD of GluA1 expresses normal LTP and spatial memory, assayed by the Morris water maze. Our results support a model in which LTP generates synaptic slots, which capture passively diffusing AMPARs. |
