First Author | Chapman VM | Year | 1991 |
Journal | Genomics | Volume | 9 |
Issue | 2 | Pages | 309-13 |
PubMed ID | 2004781 | Mgi Jnum | J:11054 |
Mgi Id | MGI:59496 | Doi | 10.1016/0888-7543(91)90258-g |
Citation | Chapman VM, et al. (1991) Linkage of the erythroid transcription factor gene (Gf-1) to the proximal region of the X chromosome of mice. Genomics 9(2):309-13 |
abstractText | We have used a cDNA probe for mouse Gf-1 gene that encodes the erythroid cell transcription factor to identify genetic variation in genomic DNA between Mus species. The segregation of Gf-1 DNA variation was analyzed in Mus species crosses that have been previously typed for the segregation of more than 30 genes spanning 80 cM of the mouse X chromosome from the centromere to the border of the X-Y pairing region. We identified a single X chromosome locus in the mouse, Gf-1, and an analysis of recombinants from 203 backcross progeny mapped Gf-1 to the proximal portion of the chromosome, coincident with the Cybb locus and proximal to Otc gene locus. A gene order of centromere, DXWas70, Cybb/Gf-1, Otc, Timp was established for the mouse X chromosome, which is in agreement with the map position observed on the human X chromosome. |