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Publication : Linkage of the erythroid transcription factor gene (Gf-1) to the proximal region of the X chromosome of mice.

First Author  Chapman VM Year  1991
Journal  Genomics Volume  9
Issue  2 Pages  309-13
PubMed ID  2004781 Mgi Jnum  J:11054
Mgi Id  MGI:59496 Doi  10.1016/0888-7543(91)90258-g
Citation  Chapman VM, et al. (1991) Linkage of the erythroid transcription factor gene (Gf-1) to the proximal region of the X chromosome of mice. Genomics 9(2):309-13
abstractText  We have used a cDNA probe for mouse Gf-1 gene that encodes the erythroid cell transcription factor to identify genetic variation in genomic DNA between Mus species. The segregation of Gf-1 DNA variation was analyzed in Mus species crosses that have been previously typed for the segregation of more than 30 genes spanning 80 cM of the mouse X chromosome from the centromere to the border of the X-Y pairing region. We identified a single X chromosome locus in the mouse, Gf-1, and an analysis of recombinants from 203 backcross progeny mapped Gf-1 to the proximal portion of the chromosome, coincident with the Cybb locus and proximal to Otc gene locus. A gene order of centromere, DXWas70, Cybb/Gf-1, Otc, Timp was established for the mouse X chromosome, which is in agreement with the map position observed on the human X chromosome.
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