First Author | Downes GB | Year | 1999 |
Journal | Genomics | Volume | 57 |
Issue | 1 | Pages | 173-6 |
PubMed ID | 10191100 | Mgi Jnum | J:54663 |
Mgi Id | MGI:1335680 | Doi | 10.1006/geno.1999.5763 |
Citation | Downes GB, et al. (1999) Chromosomal mapping of five mouse G protein gamma subunits. Genomics 57(1):173-6 |
abstractText | Heterotrimeric G proteins, composed of alpha, beta, and gamma subunits, transduce signals from transmembrane receptors to a wide range of intracellular effecters. The G protein gamma subunits, which play an indispensible role in this communication, constitute a large and diverse multigene family. Using an interspecific back cross panel, we have determined the mouse chromosomal locations of five gamma subunit genes: gamma 2, gamma 8, gamma 10, gamma 12, and gamma Cone. Combined with previous mapping studies, these data indicate that, with the possible exception of gamma 1 and gamma 11, the G protein gamma subunit genes are well dispersed within the mouse and human genomes. (C) 1999 Academic Press. |