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Allele : Tg(Chrna1)1Ekr transgene insertion 1, Ellen Kraig
Primary Identifier  MGI:2447080 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Chrna1)1Ekr
Is Recombinase  false Is Wild Type  false
molecularNote  The chicken Chrna1 promoter was used to drive expression of Torpedo californica (fish) Chrna1 cDNA in muscle tissue. The transgene construct included a spliceable intron and polyadenylation sequences from the rabbit beta globin gene. Only one founder line was generated. Transgene expression was verified by RT-PCR analysis with strong expression observed in muscle tissue. Very low levels of transgene expression was observed in the brain and thymus.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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4 Publication categories

Trail: Allele




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