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Protein Coding Gene : Dyrk3 dual-specificity tyrosine phosphorylation regulated kinase 3

Primary Identifier  MGI:1330300 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  226419
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in erythrocyte differentiation; negative regulation of DNA damage response, signal transduction by p53 class mediator; and negative regulation of apoptotic process. Predicted to be located in several cellular components, including cytoplasmic stress granule; nuclear speck; and pericentriolar material. Predicted to be active in cytoplasm; cytoskeleton; and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system gland; musculature; and nasal cavity epithelium. Orthologous to human DYRK3 (dual specificity tyrosine phosphorylation regulated kinase 3).
PHENOTYPE: Mice homozygous for a null allele exhibit increased erythropoiesis in response to chemically-induced anemia. [provided by MGI curators]
  • synonyms:
  • Dyrk3,
  • cDNA sequence BC006704,
  • MGI:2385105,
  • BC006704,
  • dual-specificity tyrosine phosphorylation regulated kinase 3

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For