| Primary Identifier | MGI:3621899 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Nos1 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 6 was removed via cre-mediated recombination. This exon encodes the heme-binding domain. RT-PCR confirmed the loss of exon 6 in mutants, demonstrating presence of some mRNA containing exon 2, but none containing exon 6. Immunohistochemistry failed to detect any staining in the cytoplasm, neurites, varicosities, cortex or striatum of mutants. |
