| Primary Identifier | MGI:7569264 | Allele Type | Transgenic |
| Attribute String | Transactivator | Gene | Tg(Gpa33-rtTAS*M2)2Lud |
| Strain of Origin | 129 x C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The M2rtTA tet transactivator is expressed in the epithelium of the intestine and colon under the control of the intestine-specific A33 promoter. The expression/activety of the transactivator is mosaic, most likely due to stochastic transgene silencing. Approximately 1 to 5 crypts in the proximal small intestine express the transgene, fewer in the distal intestine and colon. |
