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Publication : Control of morphogenesis and differentiation by HOM/Hox genes.

First Author  Botas J Year  1993
Journal  Curr Opin Cell Biol Volume  5
Issue  6 Pages  1015-22
PubMed ID  7907490 Mgi Jnum  J:19271
Mgi Id  MGI:66549 Doi  10.1016/0955-0674(93)90086-6
Citation  Botas J (1993) Control of morphogenesis and differentiation by HOM/Hox genes. Curr Opin Cell Biol 5(6):1015-22
abstractText  HOM/Hox genes are master regulatory switches that specify axial identity and control the growth and differentiation of groups of cells related by position. HOM/Hox genes function combinatorially and hierarchically to specify cell fate. Some of the genes they regulate and that mediate specific identify functions have been identified. Research in Drosophila has shown that HOM genes are continuously required during development for correct axial identity.
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