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Allele : Mecp2<tm3.1Bird> methyl CpG binding protein 2; targeted mutation 3.1, Adrian Bird
Primary Identifier  MGI:4938309 Allele Type  Targeted
Attribute String  Reporter Gene  Mecp2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting construct was designed to insert an enhanced green fluorescent protein sequence (EGFP) sequence (preceded by sequence for linker peptide CKDPPVAT) and a loxP-flanked neomycin (neo) resistance sequence-STOP cassette in the 3' UTR. Subsequent cre-mediated recombination removed the floxed neo-STOP cassette. This allele expresses a chimeric protein with the EGFP peptide linked to the C-terminus of the endogenous peptide.
  • mutations:
  • Insertion
  • synonyms:
  • MECP2-EGFP,
  • MECP2-EGFP
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

15 Publication categories

Trail: Allele




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