| Primary Identifier | MGI:1098824 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 18286 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable small GTPase binding activity. Predicted to be involved in cilium organization and regulation of cilium assembly. Located in microtubule organizing center and sperm flagellum. Part of ciliary transition fiber. Is expressed in several structures, including brain; early conceptus; inner ear; liver; and reproductive system. Orthologous to human ODF2 (outer dense fiber of sperm tails 2). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit embryonic lethality before implantation and transmission ratio distortion while all heterozygous males display normal development and fertility. Males heterozygous for other alleles are either infertile or show reduced fertility. [provided by MGI curators] |