Primary Identifier | MGI:4436716 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Fgf21 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Part of exon 1, all of exon 2 and the 5' region of exon 3 were replaced by a neomycin cassette by homologous recombination. Quantitative PCR confirmed the absence of product in the liver, perigonadal white adipose tissue and brown adipose tissue of ketogenetic diet fed homozygous mice . |