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Allele : Fgf21<tm1Emf> fibroblast growth factor 21; targeted mutation 1, Eleftheria Maratos-Flier

Primary Identifier  MGI:4436716 Allele Type  Targeted
Attribute String  Null/knockout Gene  Fgf21
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Part of exon 1, all of exon 2 and the 5' region of exon 3 were replaced by a neomycin cassette by homologous recombination. Quantitative PCR confirmed the absence of product in the liver, perigonadal white adipose tissue and brown adipose tissue of ketogenetic diet fed homozygous mice .
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

15 Publication categories

Trail: Allele