Primary Identifier | MGI:3621893 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Lrp4 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The locus was disrupted by the insertion of a stop codon just upstream of the transmembrane segment. Part of exon 36 and 2.1 kb of intron 36 were replaced with a neomycin resistance cassette. RT-PCR confirmed the complete lack of functional transcripts. |