Primary Identifier | MGI:1921575 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 74325 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable clathrin heavy chain binding activity and peptide binding activity. Predicted to be involved in clathrin-dependent endocytosis. Located in ciliary membrane and trans-Golgi network. Is expressed in central nervous system; dorsal root ganglion; liver; and neural retina. Orthologous to human CLTB (clathrin light chain B). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal synaptic vesicle recycling and increased synaptic vesicle number with no apparent defects in neurotransmission, survival or motor coordination. [provided by MGI curators] |