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Protein Domain : Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1/2

Primary Identifier  IPR026722 Type  Family
Short Name  NYAP1/NYAP2
description  This entry includes NYAP1 and NYAP2 from neuronal tyrosine-phosphorylated adaptor for the PI 3-kinase (NYAP) family (consists of NYAP1, NYAP2, NAP3/Myosin16). NYAPs activate PI3K in PI3K pathway, whichis a fundamental pathway for various cellular events in neurons. They also interact with components of the WAVE1 complex, which mediates actin cytoskeleton remodeling through Arp2/3 complex. It was suggested that NYAPs connect PI3K activation to WAVE1 signalling in neurons[].

2 Child Features

0 Parent Features

8 Protein Domain Regions