Primary Identifier | MGI:1888499 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 55985 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables CXCR5 chemokine receptor binding activity and chemokine activity. Involved in several processes, including B cell chemotaxis across high endothelial venule; activation of GTPase activity; and lymph node development. Located in extracellular space. Is expressed in Peyer's patch; aorta; central nervous system; and retina. Orthologous to human CXCL13 (C-X-C motif chemokine ligand 13). PHENOTYPE: B lymphocyte trafficking is impaired in homozygous mutant mice. [provided by MGI curators] |