First Author | Dhar MS | Year | 2004 |
Journal | DNA Seq | Volume | 15 |
Issue | 4 | Pages | 306-9 |
PubMed ID | 15620220 | Mgi Jnum | J:95896 |
Mgi Id | MGI:3527945 | Doi | 10.1080/10425170412331279855 |
Citation | Dhar MS, et al. (2004) Physical mapping of the pink-eyed dilution complex in mouse chromosome 7 shows that Atp10c is the only transcript between Gabrb3 and Ube3a. DNA Seq 15(4):306-9 |
abstractText | Phenotypic analyses of a set of homozygous-lethal deletion mutants at the pink-eyed dilution (p) locus has resulted in the identification of p-linked obesity locus 1 (plo 1), distal to the p locus, as a locus involved in the modulation of body fat and/or affecting lipid metabolism in these mice. The plo 1 region maps to mouse chromosome 7 (MMU 7) between two genes, Gabrb3 and Ube3a, which have been used as anchor points to generate an integrated deletion and physical map of plo 1 that encompasses about 1.2-1.3 Mb. A deletion/physical map was constructed and the genomic DNA between the two loci was sequenced to identify genes mapping to this region. Data show that Atp10c, a novel type IV ATPase a putative phospholipid transporter, is the only coding unit in this region of the chromosome. |