Primary Identifier | MGI:2385007 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 223255 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including execution phase of apoptosis; intrinsic apoptotic signaling pathway in response to oxidative stress; and positive regulation of axon regeneration. Predicted to act upstream of or within apoptotic process. Predicted to be located in Golgi membrane; cytosol; and nucleolus. Predicted to be active in Golgi apparatus. Is expressed in central nervous system and neural retina. Orthologous to human STK24 (serine/threonine kinase 24). PHENOTYPE: A hypomorphic mutation increases degranulation of, and exocytosis by, neutrophils. [provided by MGI curators] |