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Allele : Mapt<tm1(MAPT*P301L)Tmi> microtubule-associated protein tau; targeted mutation 1, Tomohiro Miyasaka
Primary Identifier  MGI:6389830 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Mapt
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Human tau cDNA containing the P301L mutation and a floxed PGK-Neo poly-A cassette were inserted in-frame from the endogenous start codon in exon 1 of the gene. The mutant human tau replaces the endogenous mouse tau and is expressed under the mouse tau promoter.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • P301L KI,
  • P301L KI
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele




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