| First Author | Yuan TL | Year | 2013 |
| Journal | Cancer Cell | Volume | 24 |
| Issue | 5 | Pages | 562-3 |
| PubMed ID | 24229705 | Mgi Jnum | J:206739 |
| Mgi Id | MGI:5551927 | Doi | 10.1016/j.ccr.2013.10.015 |
| Citation | Yuan TL, et al. (2013) Killing tumors by keeping ras and PI3' kinase apart. Cancer Cell 24(5):562-3 |
| abstractText | Ras proteins mediate PI3K activation through direct binding to p110 catalytic subunits. However, it is unclear when and where this interaction occurs. In this issue of Cancer Cell, Castellano and colleagues report that KRAS-driven lung cancers require the Ras-p110alpha interaction for full activation of PI3K and tumor maintenance. |
