Primary Identifier | MGI:1340034 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 20349 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables semaphorin receptor binding activity. Involved in several processes, including angiogenesis; negative regulation of angiogenesis; and negative regulation of cell-matrix adhesion. Located in extracellular space. Is expressed in several structures, including cochlea; embryo mesenchyme; hemolymphoid system gland; nervous system; and nose. Orthologous to human SEMA3E (semaphorin 3E). PHENOTYPE: Homozygous null mice display abnormal intersomitic vacular development and loss of the normal segmented somite pattern. Homozygous mutants for another allele have Bergmeister papillae on the surface of the optic disc. [provided by MGI curators] |