Primary Identifier | MGI:2681955 | Allele Type | Chemically induced (ENU) |
Attribute String | Null/knockout | Gene | Gtpbp2 |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
molecularNote | This ENU-induced T to C point mutation in the consensus splice donor site of intron 6 results in misspliced mRNAs with premature stop codons. Western blot analysis failed to detect this protein in cerebellar extracts from homozygotes. |