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Protein Coding Gene : Hacd1 3-hydroxyacyl-CoA dehydratase 1
Primary Identifier  MGI:1353592 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  30963
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable enzyme binding activity; hydroxyapatite binding activity; and very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity. Acts upstream of or within myotube differentiation; regulation of G1/S transition of mitotic cell cycle; and regulation of G2/M transition of mitotic cell cycle. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; embryo mesenchyme; lung; musculature; and nervous system. Human ortholog(s) of this gene implicated in congenital myopathy. Orthologous to human HACD1 (3-hydroxyacyl-CoA dehydratase 1).
PHENOTYPE: Homozygous knockout leads to decreased body size and weight and reduced skeletal muscle weight. [provided by MGI curators]
  • synonyms:
  • Ptpla,
  • protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a,
  • 3-hydroxyacyl-CoA dehydratase 1,
  • Hacd1
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Canonical gene --> CDSs in specific strains.

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Trail: ProteinCodingGene

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