First Author | Nosten M | Year | 1988 |
Journal | Physiol Behav | Volume | 43 |
Issue | 2 | Pages | 167-71 |
PubMed ID | 3212052 | Mgi Jnum | J:24860 |
Mgi Id | MGI:72600 | Doi | 10.1016/0031-9384(88)90233-8 |
Citation | Nosten M, et al. (1988) Uterine and cytoplasmic effects on pup eyelid opening in two inbred strains of mice. Physiol Behav 43(2):167-71 |
abstractText | Age at Eyelid Opening (AEO) differs in two inbred strains of laboratory mice: NZB and CBA/H. Ovarian transplantation and fostering methods were employed to test for variation of genotypic expression in different environments. (1) A global maternal effect was demonstrated for AEO in parental and F1 pups. (2) AEO of H and N pups is not affected by the parental vs. F1 modification of post-natal maternal environment. (3) The genotype of the mother, via uterine environment, interacts with pup genotype: only the CBA/H strain reacts to the parental vs. F1 modification in uterine environment. (4) A cytoplasmic effect for AEO was successfully replicated. Additional analyses demonstrate that AEO is not cytoplasmically inherited but rather modulated by the cytoplasmic environment. |