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Allele : Hmgcs2<em1Arima> 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2; endonuclease-mediated mutation 1, Yuichiro Arima

Primary Identifier	MGI:7432780	Allele Type	Endonuclease-mediated
Attribute String	Conditional ready	Gene	Hmgcs2
Strain of Origin	C57BL/6	Is Recombinase	false
Is Wild Type	false

molecularNote

Using the CRISPRâCas9 system, exon 2 of the Hmgcs2 gene was flanked by the loxP sequences.

mutations:
Insertion

synonyms:
Hmgcs2-floxed,
Hmgcs2-floxed

earliestPublication:
Arima Y, et al. (2021) Murine neonatal ketogenesis preserves mitochondrial energetics by preventing protein hyperacetylation. Nat Metab 3(2):196-210

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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