Primary Identifier | MGI:1334419 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 11801 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within positive regulation of complement-dependent cytotoxicity and regulation of complement activation. Located in cell surface and plasma membrane. Is expressed in several structures, including central nervous system; immune system; liver; retina; and testis. Orthologous to human CD5L (CD5 molecule like). PHENOTYPE: Homozygous null mice exhibit enhanced and prolonged bacterial-induced granuloma formation and increased apoptosis of NKT and T cells. [provided by MGI curators] |