First Author | Madsen AN | Year | 2003 |
Journal | J Virol | Volume | 77 |
Issue | 22 | Pages | 12378-84 |
PubMed ID | 14581577 | Mgi Jnum | J:86327 |
Mgi Id | MGI:2679411 | Doi | 10.1128/JVI.77.22.12378-12384.2003 |
Citation | Madsen AN, et al. (2003) Role of macrophage inflammatory protein-1alpha in T-cell-mediated immunity to viral infection. J Virol 77(22):12378-84 |
abstractText | The immune response to lymphocytic choriomeningitis virus in mice lacking macrophage inflammatory protein-1alpha (MIP-1alpha) was evaluated. Generation of virus-specific effector T cells is unimpaired in MIP-1alpha-deficient mice. Furthermore, MIP-1alpha is not required for T-cell-mediated virus control or virus-induced T-cell-dependent inflammation. Thus, MIP-1alpha is not mandatory for T-cell-mediated antiviral immunity. |