Primary Identifier | MGI:1860494 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 56200 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Enables double-stranded RNA binding activity and identical protein binding activity. Involved in positive regulation of canonical NF-kappaB signal transduction and positive regulation of myeloid dendritic cell cytokine production. Acts upstream of or within response to exogenous dsRNA and response to virus. Located in cytosol. Is expressed in several structures, including 1st branchial arch; cerebral cortex; early conceptus; genitourinary system; and limb. Orthologous to human DDX21 (DExD-box helicase 21). PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit embryonic lethality. [provided by MGI curators] |