First Author | van den Ouweland AM | Year | 1992 |
Journal | Hum Mol Genet | Volume | 1 |
Issue | 4 | Pages | 269-73 |
PubMed ID | 1303197 | Mgi Jnum | J:26807 |
Mgi Id | MGI:74238 | Doi | 10.1093/hmg/1.4.269 |
Citation | van den Ouweland AM, et al. (1992) Identification and characterization of a new gene in the human Xq28 region. Hum Mol Genet 1(4):269-73 |
abstractText | A human Xqter chromosome cosmid library was screened with a mixed probe derived from porcine kidney mRNA. A new expressed gene was identified in a cosmid clone known to be part of a G6PD cosmid contig. This gene is most likely a housekeeping gene because the cDNA clone recognizes a 1 kb mRNA transcript in all cell lines and tissues tested. Hybridizing genomic DNA of several species with a cDNA probe indicated that the gene is highly conserved during evolution and that it belongs to a gene family. The genomic sequence shows a 100% homology with the recently identified QM cDNA sequence. |