Primary Identifier | MGI:109517 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 20389 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable identical protein binding activity. Located in cytoplasm and extracellular region. Is expressed in several structures, including lung; lung surfactant; and main bronchus epithelium. Used to study desquamative interstitial pneumonia. Human ortholog(s) of this gene implicated in asthma; lung disease (multiple); and respiratory syncytial virus infectious disease. Orthologous to human SFTPC (surfactant protein C). PHENOTYPE: Mice homozygous for disruptions in this gene display respiratory abnormalities similar to emphysema. [provided by MGI curators] |