| First Author | Saffer JD | Year | 1990 |
| Journal | Genomics | Volume | 8 |
| Issue | 3 | Pages | 571-4 |
| PubMed ID | 1981055 | Mgi Jnum | J:10995 |
| Mgi Id | MGI:59437 | Doi | 10.1016/0888-7543(90)90046-w |
| Citation | Saffer JD, et al. (1990) Localization of the gene for the trans-acting transcription factor Sp1 to the distal end of mouse chromosome 15. Genomics 8(3):571-4 |
| abstractText | The mouse chromosomal location for the gene (Sp1-1) encoding the trans-acting transcription factor Sp1 has been determined. Analysis of restriction fragment length polymorphisms in recombinant inbred, congenic, and interspecific backcross mice using human and mouse cDNA probes demonstrated that Sp1-1 is a single gene closely linked to the mammary tumor virus integration site-1 (Int-1) on the distal end of chromosome 15. Sp1 is a zinc finger protein, but Sp1-1 is not closely linked to any of the other zinc finger protein genes that have been mapped in mouse. Int-1 and other markers flanking the Sp1-1 locus are part of a conserved linkage group represented on human chromosome 12q. |
