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Protein Coding Gene : Bsn bassoon

Primary Identifier  MGI:1277955 Organism  Mus musculus
Chromosome  9 NCBI Gene Number  12217
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 5.4.0)

A structural constituent of presynaptic active zone. Involved in several processes, including presynapse to nucleus signaling pathway; regulation of synaptic vesicle cycle; and synaptic vesicle clustering. Located in several cellular components, including cell surface; postsynaptic density; and presynaptic active zone cytoplasmic component. Is active in several cellular components, including GABA-ergic synapse; Schaffer collateral - CA1 synapse; and cochlear hair cell ribbon synapse. Is expressed in nervous system and retina. Used to study epilepsy. Orthologous to human BSN (bassoon presynaptic cytomatrix protein).
PHENOTYPE: Mutants lacking functional protein exhibit impaired hippocampal and photoreceptor synaptic transmission, aberrant photoreceptor ribbon synapse formation, and spontaneous epileptic seizures. [provided by MGI curators]
  • synonyms:
  • bassoon,
  • presynaptic cytomatrix protein,
  • Bsn

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

664 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications