| Primary Identifier | MGI:95420 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 13884 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables carboxylesterase activity. Acts upstream of or within response to bacterium. Located in extracellular space. Is expressed in several structures, including alimentary system; liver; nose; respiratory system; and urinary system. Human ortholog(s) of this gene implicated in colorectal cancer and gastrointestinal system cancer. Orthologous to human CES1 (carboxylesterase 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit protection against nerve agents such as chlorpyrifos and chlorpyrifos oxon but increased sensitivity to soman coumarin. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
