| First Author | Otto J | Year | 1983 |
| Journal | Biochem Genet | Volume | 21 |
| Issue | 1-2 | Pages | 37-48 |
| PubMed ID | 6838491 | Mgi Jnum | J:7041 |
| Mgi Id | MGI:55512 | Doi | 10.1007/BF02395390 |
| Citation | Otto J, et al. (1983) Esterase-17 (ES-17): characterization and genetic location on chromosome 9 of a bis-p-nitrophenyl phosphate-resistant esterase of the house mouse (Mus musculus). Biochem Genet 21(1-2):37-48 |
| abstractText | Genetic variation of a new codominantly inherited esterase, designated ES-17, has been discovered in the house mouse using isoelectric focusing in polyacrylamide gels. The ES-17 A phenotype (three bands; isoelectric points, between pH 5.55 and pH 5.90) was found in C57BL/10Sn. LP/J possessed the Es-17B phenotype (three bands; isoelectric points, pH 5.05-5.55). ES-17 was present in all tissues examined, except for hemolysate and serum, and was most clearly expressed in the small intestine. Because of its reaction toward various substrates and inhibitors, ES-17 has tentatively been classified as acetyl esterase (EC 3.1.1.6). ES-17 was shown to be controlled by the structural locus Es-17, located on chromosome 9. From test-cross data, a gene order of Es-17-8.7 +/- 2.5 map units-Mpi-1-10.2 +/- 2.7 map units-Mod-1 was established. |
