| Type | MGI:General | Description | skinned and intact papillary muscle fibers exhibit abnormalities in myofilament contractility, with decrease in calcium sensitivity of force, reduced contractile force at submaximal calcium concentrations and faster (shorter time) relaxation phase of force transients cardiac myosin purified from ventricles shows hypocontractile activity reflecting a diminished ability of myosin to hydrolize ATP to produce energy for muscle contraction papillary muscle fibers exhibit less association of myosin heads with thin filaments |
