Primary Identifier | MGI:3582587 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Itgal |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A constitutive germline deletion of the amino acid motif GFFKR in the membrane proximal segment of the cytoplasmic domain, was accomplished by insertion of a neomycin resistance cassette and a HSV-thymidine kinase cassette. The neo was later removed by crossing to a cre expressing strain. |