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Allele : Itgal<tm1Hlz> integrin alpha L; targeted mutation 1, Bernhard Holzmann

Primary Identifier  MGI:3582587 Allele Type  Targeted
Attribute String  Null/knockout Gene  Itgal
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A constitutive germline deletion of the amino acid motif GFFKR in the membrane proximal segment of the cytoplasmic domain, was accomplished by insertion of a neomycin resistance cassette and a HSV-thymidine kinase cassette. The neo was later removed by crossing to a cre expressing strain.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Lfa-1<d>,
  • Lfa-1<d>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele