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Allele : Tg(ITGA2)1067Fmw transgene insertion 1067, Fiona M Watt
Primary Identifier  MGI:1926490 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(ITGA2)1067Fmw
Inheritance Mode  Not Specified Strain of Origin  (CBA x C57BL/10)F1
Is Recombinase  false Is Wild Type  false
description  See also Tg(ITGA2)1070Fmw and Tg(ITGA2)1075Fmw for variability in transgene copy number using this construct. Severity of described phenotypes correlates to the copy number of the transgenes.
molecularNote  Overexpression of human integrin alpha 2 (ITGA2) in the suprabasal layers of the epidermis driven by the human involucrin (IVL) promoter. 45 copies of this gene were inserted, as determined by southern blotting.
  • mutations:
  • Insertion
  • synonyms:
  • 1067 alpha2,
  • 1067 alpha2
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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