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Allele : Npm1<tm1Trow> nucleophosmin 1; targeted mutation 1, Jennifer Trowbridge

Primary Identifier  MGI:6285874 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence Gene  Npm1
Transmission  Germline Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting vector contains an FRT site followed by PGK-puromycin, exon 11 of the mouse Npm1 gene, a polyA sequence, and a 4xSv40pA STOP cassette and a second FRT site inserted into the exon 10 intron, upstream of a humanized copy of exon 11 incorporating a TCTG frameshift duplication (p.W288fs*12; also called Npm1c Type A).
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Npm1<frt-cA>,
  • Npm1<frt-cA>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele