| Type | MGI:General | Description | mutant sternomastoid neuromuscular junctions (NMJs) display shallow nerve gutters, postjunctional folds that appear less organized and have fewer openings to the synaptic cleft than controls, synaptic acetylcholine receptors (AChRs) separated into distinct clusters, and perisynaptic clusters of AChR extending beyond identifiable nerve-muscle contacts mutant neuromuscular junctions have undetectable levels of postsynaptic utrophin and show a significant reduction in AChR (65%) and acetylcholinesterase (55%) levels relative to wild-type controls some NMJs display these features over their entire extent, whereas others show areas of aberrant AChR pattern adjacent to normally appearing areas |
