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Publication : A major messenger ribonucleic acid of the rodent epididymis encodes a small glycosylphosphatidylinositol-anchored lymphocyte surface antigen.

First Author  Kirchhoff C Year  1994
Journal  Biol Reprod Volume  50
Issue  4 Pages  896-902
PubMed ID  7515288 Mgi Jnum  J:36535
Mgi Id  MGI:84065 Doi  10.1095/biolreprod50.4.896
Citation  Kirchhoff C (1994) A major messenger ribonucleic acid of the rodent epididymis encodes a small glycosylphosphatidylinositol-anchored lymphocyte surface antigen. Biol Reprod 50(4):896-902
abstractText  The adult rodent epididymis and seminal vesicles were shown by polymerase chain reaction (PCR) cloning. Northern blot analysis, and in situ hybridization to be major expression sites of an mRNA encoding a small glycosylphosphatidylinositol (GPI)-anchored cell surface antigen that has been previously described as the mouse lymphocyte differentiation antigen B7, herein referred to as MB7. Sequence comparison of the corresponding epididymal cDNAs from the mouse (MB7) and the rat (RB7) revealed an unexpected divergence in the peptide coding regions of these homologous genes. A possible functional relationship to the human sperm surface and lymphocyte differentiation antigen CDw52/HE5 is discussed with respect to the highly variable mature peptide coding regions.
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